Modulation of Brain Reactivity to Drug-Related cues

Modulation of Brain Reactivity to Drug-Related Cues in Recently Abstinent Heroin-Dependent Patients

This study investigated the acceptance of a form of depot naltrexone (XRNT – extended-release naltrexone) among Dutch healthcare professionals in addiction care (doctors, psychologists, nurses) as a new treatment option for chronic heroin-dependent patients.

Additionally, the feasibility of XRNT as a treatment option was explored in terms of willingness to start this type of treatment, by conducting an opinion survey among chronic heroin-dependent patients.

Finally, a small clinical trial with XRNT was conducted in heroin-dependent patients in this study, examining the mechanism of action of XRNT using brain scans (pharmacofMRI and SPECT).